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Modulation of FGF Pathway Signaling and Vascular Differentiation Using Designed Oligomeric Assemblies

Natasha I. Edman,Ashish Phal,Rachel L. Redler,Thomas Schlichthaerle,Sanjay R. Srivatsan,Devon Duron Ehnes,Ali Etemadi,Seong J. An,Andrew Favor,Zhe Li,Florian Praetorius, Max Gordon,Thomas Vincent,Silvia Marchiano, Leslie Blakely,Chuwei Lin,Wei Yang,Brian Coventry,Derrick R. Hicks,Longxing Cao,Neville Bethel,Piper Heine,Analisa Murray,Stacey Gerben,Lauren Carter,Marcos Miranda,Babak Negahdari,Sangwon Lee,Cole Trapnell,Ying Zheng, Charles E. Murry,Devin K. Schweppe,Benjamin S. Freedman,Lance Stewart,Damian C. Ekiert,Joseph Schlessinger,Jay Shendure,Gira Bhabha,Hannele Ruohola-Baker,David Baker

CELL（2024）

Cited 37|Views69
Key words
de novo protein design,oligomeric scaffolds,binder design,FGF signaling,cryo-EM,endothelial cell differentiation,iPSCs,vascular development
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