Porphyromonas gingivalis triggers inflammation in hepatocyte depend on ferroptosis via activating the NF-κB signaling pathway.

Chao Yao,Dongmei Lan,Xue Li,Yan Wang,Shengcai Qi

Oral diseases（2023）

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摘要

Porphyromonas gingivalis can induce ferroptosis and inflammation in hepatocytes and further worsen liver lesions. The mechanism of ferroptosis in hepatocytes depends on NF-κB signaling pathway, which provides a new strategy for clinical treatment and prevention of NAFLD.

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关键词

Porphyromonas gingivalis ,NAFLD,NF-κB signaling pathway,ferroptosis

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