Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice.

Guo-Kun Zhou,Wen-Jing Xu,Yi Lu,Yan Zhou,Chen-Zhang Feng,Jiang-Tao Zhang,Shi-Yu Sun,Ruo-Meng Wang,Tong Liu,Bin Wu

Frontiers in molecular neuroscience（2023）

引用 0|浏览2

暂无评分

摘要

Collectively, these results provide evidence that agmatine is a novel mediator of itch and induces itch via the activation of ASIC3. Targeting neuronal ASIC3 signaling may represent a novel strategy for the treatment of itch.

查看译文

关键词

ASIC3,agmatine,atopic dermatitis,itch,pain

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要