Glucagon-Like Peptide-1 Receptor Agonist Protects Against Diabetic Cardiomyopathy by Modulating microRNA-29b-3p/SLMAP.

Ping Fang,Zhengqin Ye,Ran Li,Dunmin She,Guannan Zong,Liya Zhang,Ying Xue,Keqin Zhang

Drug design, development and therapy（2023）

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摘要

SLMAP may play roles in the pathogenesis of DCM and may be a target of GLP-1RA in protecting against DCM. After binding to myocardial GLP-1R, GLP-1RA can regulate the expression of myocardial SLMAP through miR-29b-3p.

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关键词

diabetic cardiomyopathy,glucagon-like peptide-1 receptor agonist,microRNA-29b-3p,proteomics,sarcolemmal membrane-associated protein

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