A Plantaginis Semen-Coptidis Rhizoma compound alleviates type 2 diabetic mellitus in mice via modulating AGEs-RAGE pathway.

Pei Liu,Xing Yan, Jiaying Pu,Qi Liao,Kang Wang,Jiping Lan,Rui Wang,Zhengtao Wang,Lili Ding,Li Yang

Journal of ethnopharmacology（2023）

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摘要

Our results indicated that CQC could improve the metabolic disorders of T2DM and it is a promising TCM compound for the treatment of T2DM. The potential mechanism may probably involve the regulation of the AGEs/RAGE signaling pathway.

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关键词

AGE/RAGE signaling Pathway,Chinese medicine,Network pharmacology,Plantaginis Semen-Coptidis Rhizoma Compound,Type 2 diabetic mellitus

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