The Who, What, When and Where of Inpatient Direct Oral Penicillin Challenge - Implications for health services implementation.

J A Trubiano,S Vogrin,E Mitri, R Hall,A Copaescu, J Waldron,J De Luca,M Rose, G Mackay, B Lambros,A P Douglas,N E Holmes,K Y L Chua

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial stewardship (AMS) initiatives to reduce the burden and impacts of penicillin allergy labels on antibiotic prescribing. Using data from a prospective multicentre cohort inpatient penicillin allergy program, we identify the key targets for delabeling to aid health service implementation.

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关键词

amoxicillin allergy,antimicrobial stewardship,beta-lactam allergy,drug allergy,oral provocation

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