Association between childhood trauma and white matter deficits in first-episode schizophrenia.

Min Xie,Jia Cai,Yunjia Liu,Wei Wei,Zhengyang Zhao,Minhan Dai,Yulu Wu,Yunqi Huang,Yiguo Tang,Liling Xiao,Guangya Zhang,Chuanwei Li,Wanjun Guo,Xiaohong Ma,Wei Deng,Xiangdong Du,Qiang Wang,Tao Li

Psychiatry research（2023）

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摘要

This study demonstrates that individuals with FES evince widespread cerebral WM abnormalities and that these abnormalities were associated with ChT. These results provide clues about the neural basis and potential biomarkers of schizophrenia.

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关键词

Childhood trauma,Diffusion tensor imaging,First-episode schizophrenia,White matter

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