Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.

Junhui He, Dongbo Han,Chunlian Jia,Jiaxiu Xie, Fucui Zhu,Jie Wei,Dongmei Li,Dongmei Wei,Yi Li,Li Tang,Guining Wei, Jing Yan,Yuanming Tong,Lifang Yang, Xuecai Tan

Drug design, development and therapy（2023）

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摘要

AFPR may exert antidepressant effects through multiple components, targets and pathways. Furthermore, it could improve neuroplasticity via the cAMP signaling pathway to improve depression-like symptoms.

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关键词

BDNF,CAMP signaling pathway,GC-MS,PC12 cells,corticosterone

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