Esophageal cancer-related gene 4 inhibits gastric cancer growth and metastasis by upregulating Krüppel-like factor 2 expression.

Ximei Li,Shengjuan Hu,Meijuan Ma,Pengda Wang,Yao Qi,Yan Zhou,Zishao Zhong,Hengjun Gao,Feihu Bai

Annals of translational medicine（2023）

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摘要

Our findings show that ECRG4 promotes GC progression via Krüppel-like factor 2 signaling and highlight ECRG4 as a potential GC biomarker and therapeutic target.

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关键词

Esophageal cancer-related gene 4 (ECRG4),Krüppel-like factor 2 (KLF2),clinicopathological parameters,gastric cancer (GC),prognosis

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