Hair cortisol concentrations and perceived stress in 7-year-old children at familial high-risk of schizophrenia or bipolar disorder.

Julie Marie Brandt,Nicoline Hemager,Ditte Ellersgaard,Maja Gregersen,Anne Søndergaard,Jessica Ohland,Katrine Søborg Spang,Camilla Christiani,Birgitte Klee Burton,Aja Greve,Carsten Hjorthøj,Ole Mors,Kerstin Jessica Plessen,Jens Richardt Møllegaard Jepsen,Merete Nordentoft,Anne Amalie Elgaard Thorup

Progress in neuro-psychopharmacology & biological psychiatry（2023）

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摘要

Children at FHR-SZ and FHR-BP did not exhibit higher levels of hair cortisol concentrations at age 7, while both FHR-groups had higher level of self-reported perceived stress compared with controls. Early attention to stress in children at FHR is crucial and these vulnerabilities should be targeted in future interventions studies.

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关键词

Bipolar disorder,Familial high-risk,Hair cortisol,Perceived stress,Schizophrenia

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