CD47 expression is critical for CAR T-cell survival in vivo.

Alex N Beckett,Peter Chockley,Shondra M Pruett-Miller,Phuong Nguyen,Peter Vogel,Heather Sheppard,Giedre Krenciute,Stephen Gottschalk,Christopher DeRenzo

Journal for immunotherapy of cancer（2023）

引用 4|浏览12

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摘要

These findings highlight that CD47 expression is critical for CAR T-cell survival in vivo and is a 'sine qua non' for successful adoptive T-cell therapy.

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关键词

Receptors, Chimeric Antigen

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