Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy.
Cancer research（2023）
摘要
Targeting XRN1 activates an intracellular innate immune response mediated by RNA-sensing signaling and potentiates cancer immunotherapy efficacy, suggesting inhibition of RNA decay machinery as a novel strategy for cancer treatment.
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关键词
immunotherapy,rna,cancer
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