Life-threatening "hyper-progression" on immunotherapy revealed as pseudo-progression in DNA mismatch repair deficiency: a case report.

Mojun Zhu, Chitra Ganesan,Siobhan Flanagan,Harry H Yoon

Journal of gastrointestinal oncology（2023）

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摘要

This case demonstrates that life-threatening hyper-progression can represent pseudo-progression and suggests that MMR status could be important to consider in determining the aggressiveness of clinical management during apparent hyper-progression.

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关键词

Mismatch repair (MMR),case report,hyper-progression,immune checkpoint inhibitor (ICI),microsatellite instability,pseudo-progression

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