Real pandemic world results of pharmacokinetic-tailored personalized prophylaxis of bleeds in Polish children and adolescents with severe hemophilia A.

Frontiers in pediatrics（2023）

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摘要

(1) Switching from pdFVIII to rFVIII (octocog-alpha) in PTPs with sHA is safe, (2) PK-based personalized prophylaxis may decrease ABR and AJBR in children and adolescents with sHA.

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关键词

annualized bleeding rate,annualized joint bleeding rate,bleeding prophylaxis,children,hemophilia A,plasma-derived FVIII,recombinant FVIII

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