Upregulation of APOC1 Promotes Colorectal Cancer Progression and Serves as a Potential Therapeutic Target Based on Bioinformatics Analysis.

Weiwei Tang,Hanyuan Liu,Xiao Li,Theng Choon Ooi,Nor Fadilah Rajab,Hongyong Cao,Razinah Sharif

Journal of oncology（2023）

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摘要

Based on scRNA-seq research, the current study shows that APOC1 was overexpressed in TAMs from CRC tissues. By inhibiting APOC1 in TAMs, CRC progression was reduced in vitro, offering a new tactic and giving CRC patients fresh hope.

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关键词

colorectal cancer,bioinformatics analysis

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