Maternal diet during gestation affect prostatic tissue component in SHR/Izm offspring

Shibamori K.,Kyoda Y.,Shindo T., Maehana T., Nishida S.,Hashimoto K.,Kobayashi K.,Tanaka T., Suzuki H.,Masumori N.

European Urology（2023）

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摘要

Our findings suggest that both maternal undernutrition and obesity influence the prostatic development of offspring. Maternal consumption of a low protein diet promotes epithelial hyperplasia through the upregulation of apoptosis inhibitors, while a high fat diet leads to increased stromal growth through the induction of EMT.

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prostatic tissue component,maternal diet,gestation

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