Neuroregeneration and immune response after neurorrhaphy are improved with the use of heterologous fibrin biopolymer in addition to suture repair alone.

Felipe Cantore Tibúrcio,Kevin Silva Muller,Ana Paula Silveira Leite, Igor Rodrigues Araújo de Oliveira,Benedito Barraviera,Rui Seabra Ferreira,Carlos Roberto Padovani,Carina Guidi Pinto,Selma Maria Michelin Matheus

Muscle & nerve（2023）

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摘要

HFB potentiates the immune response, increases axonal regeneration, induces angiogenesis, prevents severe muscle degeneration, and assists in NMJ recovery. In conclusion, suture-associated HFB has major implications for improved peripheral nerve repair.

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关键词

heterologous fibrin sealant,immune response,nerve regeneration,neuromuscular junction,peripheral nerve injury

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