Associations of pre- and postnatal exposures with optic nerve status in young adults.

Linna Zhu,Inger Christine Munch,Casper-Emil T Pedersen,Jakob Stokholm,Klaus Bønnelykke,Bo Chawes,Christian Jakob Carlsson,Ann-Marie M Schoos,Michael Larsen,Hans Bisgaard,Nicklas Brustad

Acta ophthalmologica（2023）

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摘要

We found that exposure to smoking during early life was associated with a thinner RNFL and macula at age 18 years. The absence of an association between active smoking at 18 years suggests that the vulnerability of the optic nerve is highest during prenatal life and early childhood.

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PM2.5,alcohol,asthma,corticosteroids,macular thickness,optical coherence tomography,retinal nerve fibre layer,smoking

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