RIFM fragrance ingredient safety assessment, 2-methoxy-3(5 and 6)-iso-propylpyrazine, CAS Registry Number 25773-40-4

A. M. Api,D. Belsito, D. Botelho, M. Bruze,G. A. Burton,M. A. Cancellieri,H. Chon,M. L. Dagli, W. Dekant,C. Deodhar, A. D. Fryer, L. Jones,K. Joshi,M. Kumar,A. Lapczynski,M. Lavelle, I. Lee,D. C. Liebler,H. Moustakas, J. Muldoon, M. Na, T. M. Penning, G. Ritacco, J. Romine, N. Sadekar, T. W. Schultz, D. Selechnik, F. Siddiqi, I. G. Sipes,G. Sullivan, Y. Thakkar, Y. Tokura

FOOD AND CHEMICAL TOXICOLOGY（2023）

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摘要

•2-Methoxy-3(5 and 6)-isopropylpyrazine; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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