In utero exposure to antiemetic and risk of adult-onset colorectal cancer.

Caitlin C Murphy,Piera M Cirillo,Nickilou Y Krigbaum,Amit G Singal,Barbara A Cohn

JNCI cancer spectrum（2023）

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摘要

Higher risk of CRC in offspring exposed in utero may be driven by dicyclomine contained in the 3-part formulation of Bendectin used during the 1960s. Experimental studies are needed to clarify these findings and identify mechanisms of risk.

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关键词

birth cohort,colorectal cancer,risk factor,young adult

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