MRI detection of brain gadolinium retention in multiple sclerosis: Magnetization transfer vs. T1-weighted imaging.

Carmen Cananau,Yngve Forslin,Åsa Bergendal,Henrik Sjöström,Katharina Fink,Russell Ouellette,Maria Kristoffersen Wiberg,Sten Fredrikson,Tobias Granberg

Journal of neuroimaging : official journal of the American Society of Neuroimaging（2023）

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摘要

Conventional T1-weighted imaging provided dose-dependent associations with gadolinium administrations in MS, while these could not be detected with 2-dimensional MT. Future studies could explore newer MT techniques like 3D and inhomogenous MT. Notably, these associations were identified with conventional MRI even though most patients had not received gadolinium administrations in the preceding 9 years, suggestive of long-term retention.

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关键词

gadolinium deposition,gadolinium retention,gadolinium-based contrast agents,magnetic resonance imaging,magnetization transfer,multiple sclerosis

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