Limonin counteracts obesity by activating thermogenesis in brown and white adipose tissues

Journal of Functional Foods(2023)

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摘要
•Limonin markedly decreases body weight gain, alleviates fatty liver and hyperlipidemia in obese mice.•Limonin prevents the whitening of BAT and promotes the browning of iWAT in obese mice.•Limonin promotes the adipocyte thermogenic program.•Limonin induces transcriptional coactivator PGC-1α in BAT and iWAT.
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关键词
Limonin,Obesity,Brown adipose tissue,White adipose tissues,Thermogenesis
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