Synthesis and biological properties of palladium(II) cyclometallated compounds derived from (E)-2-((4-hydroxybenzylidene)amino)phenol

Joan Albert,Basma Al Janabi,Jaume Granell,Mojdeh Sadat Hashemi,Daniel Sainz,M. Kaleem Khosa,Carme Calvis,Ramon Messeguer,Laura Baldomà,Josefa Badia,Mercè Font-Bardia

Journal of Organometallic Chemistry（2023）

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摘要

•Synthesis and characterization of palladium(II) cyclometallated compounds containing an endo-κ3-Cortho,N,Oortho tridentate chelating iminophenol ligand.•Fused five-membered metallacycles.•Anticancer, antibacterial and antioxidant activities.•DNA binding and topoisomerase II⍺ inhibition.

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关键词

Cyclometallation,Palladium(II),Iminophenol,Anticancer,Antibacterial,Antioxidant

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