Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S.

Boyun Shi,Wei Wang,Mengting Ye,Min Liang,Ziyu Yu,Yingying Zhang,Zhaoyu Liu,Xue Liang,Jian Ao, Fengfeng Xu,Guibin Xu,Xianhan Jiang,Xinke Zhou,Leyuan Liu

Liver international : official journal of the International Association for the Study of the Liver（2023）

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摘要

Spermidine supplementation is a potentially clinically meaningful approach to treating and curing liver fibrosis, preventing cirrhosis and HCC in patients.

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关键词

MAP1S,autophagy,extracellular matrix,hepatic stellate cells,liver fibrosis,spermidine

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