Ten-year survival of children with trisomy 13 or trisomy 18: a multi-registry European cohort study.

Svetlana V Glinianaia,Judith Rankin,Joachim Tan,Maria Loane,Ester Garne,Clara Cavero-Carbonell,Hermien E K de Walle,Miriam Gatt,Mika Gissler,Kari Klungsøyr,Natalie Lelong,Amanda Neville,Anna Pierini,David F Tucker,Stine Kjaer Urhoj,Diana Gay Wellesley,Joan K Morris

Archives of disease in childhood（2023）

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摘要

This multi-registry European study found that despite extremely high neonatal mortality in children with T13 and T18, 32% and 21%, respectively, of those who survived to 4 weeks were likely to survive to age 10 years. These reliable survival estimates are useful to inform counselling of parents after prenatal diagnosis.

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Child Health,Epidemiology,Genetics,Mortality,Syndrome

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