Alterations of pain pathways by experimental sleep disturbances in humans: Central pain-inhibitory, cyclooxygenase, and endocannabinoid pathways.

Sleep(2023)

引用 5|浏览16
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摘要
These findings suggest that central pain-inhibitory COX mechanisms through which sleep disturbances may contribute to chronic pain risk are sex specific, implicating the need for sex-differential therapeutic targets to effectively reduce chronic pain associated with sleep disturbances in both sexes.
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关键词
Sleep disturbance,central pain modulation,cyclooxygenase,endocannabinoids,pain mechanisms,sex differences
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