Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer.

Martin Sjöström,Anthony Fyles,Fei-Fei Liu,David McCready,Wei Shi,Katrina Rey-McIntyre,S Laura Chang,Felix Y Feng,Corey W Speers,Lori J Pierce,Erik Holmberg,Mårten Fernö,Per Malmström,Per Karlsson

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要

The novel POLAR genomic signature on the basis of LRR biology may identify patients with a low risk of LRR despite not receiving RT, and thus may be candidates for RT omission.

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关键词

local adjuvant radiation,breast cancer,genomic profile

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