The role of PIVKA-II in hepatocellular carcinoma surveillance in an Asian population.

Wai Yoong Ng,Daniel Yan Zheng Lim,Si Yu Tan,Jason Pik Eu Chang,Thinesh Lee Krishnamoorthy,Chee Hooi Lim,Damien Meng Yew Tan,Victoria Sze Min Ekstrom,George Boon Bee Goh,Mark Chang Chuen Cheah,Rajneesh Kumar,Chin Pin Yeo,Chee Kiat Tan

Annals of the Academy of Medicine, Singapore（2023）

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摘要

Dear Editor, Alpha-fetoprotein (AFP) is the most established biomarker for surveillance of hepatocellular carcinoma (HCC) in at-risk individuals. However, its sensitivity and specificity are not very satisfactory.1 Protein induced by vitamin K absence or antagonist-II (PIVKA-II) is a newer biomarker for HCC but without a widely established cut-off.2,3 Recent data suggested that the cut-off may

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hepatocellular carcinoma surveillance,hepatocellular carcinoma,asian population

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