The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.

Che Zheng,Jun Ma,Jiawen Xu,Mingyang Li,Liming Wu,Yuangang Wu,Yuan Liu,Bin Shen

Orthopaedic surgery（2023）

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摘要

0 g IA TXA, 1.0 g IV TXA or 10.0 g IV EACA, as well as 30 mg/kg IV TXA or 150 mg/kg IV EACA were most effective and enough to control bleeding for patients after TKA. TXA was at least 5 times more potent than EACA.

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关键词

Bleeding,Epsilon-Aminocaproic acid,Total knee arthroplasty,Tranexamic acid,Transfusion

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