Accurate prediction of isocitrate dehydrogenase -mutation status of gliomas using SLOW-editing magnetic resonance spectroscopic imaging at 7 T MR.

Guodong Weng,Ekin Ermiş,Theoni Maragkou,Reinhardt Krcek, Philipp Reinhardt,Irena Zubak,Philippe Schucht,Roland Wiest,Johannes Slotboom,Piotr Radojewski

Neuro-oncology advances（2023）

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摘要

Depending on the pulse sequence, spectral editing can be a powerful tool for the noninvasive determination of the IDH status. SLOW-editing EPSI sequence is the preferable pulse sequence when used at 7 T for IDH-status characterization.

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关键词

1p/19q co-deletion,2-Hydroxy-glutarate (2HG),7 Tesla MR,Cystathionine,Glioma,IDH mutation,MRS spectral editing

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