GLUT10 is a novel immune regulator involved in lung cancer immune cell infiltration and predicts worse survival when transcriptionally downregulated.

Lijuan Jian,Qi Wu,Xinping Min,Bowen Li,Min Zhang,Zhiyong Wu,Xiaoping Hu,Zongli Ren,Zhiwei Wang,Zhipeng Hu

Heliyon（2023）

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摘要

By transcriptome experiments, database studies, and human sample studies, we found that GLUT10 is a new immune signaling molecule involved in tumor immunity, especially in the immune cell infiltration of lung adenocarcinoma (LUAD). GLUT10 may modulate the immune cell infiltration of LUAD via the COX-2 pathway.

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关键词

GLUT10,Immune infiltration,Immune molecule,Lung cancer,Prognosis,Tumor immunity

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