Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells.

Chiami Moyama,Mitsugu Fujita, Hitoshi Okamoto,Hiromi Ii,Susumu Nakata

Cancer genomics & proteomics（2023）

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摘要

Down-regulation of Myb mediates Stat5b-KD-induced inhibition of proliferation and induction of apoptosis in GSCs. This may represent a promising novel therapeutic strategy against glioblastoma.

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关键词

Glioblastoma stem cells,Myb,Stat5b,Wnt pathway,apoptosis

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