Congruent identification of imbalanced fibrinolysis by 2 distinct clot lysis time assays.

Ellen G Driever,Julie Brogaard Larsen,Sarah Bos,William Bernal,Anne-Mette Hvas,Ton Lisman

Research and practice in thrombosis and haemostasis（2023）

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摘要

Despite the differences in laboratory, protocol, reagents, operator, data processing, and analysis, overall conclusions on fibrinolytic capacity are similar between the 2 laboratories. With a higher concentration of tPA in the Aarhus assay, the test becomes less sensitive for the detection of hypofibrinolysis and is more sensitive to the addition of anticoagulants.

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关键词

blood coagulation tests,comparative study,fibrin clot lysis time,fibrinolysis,tissue plasminogen activator

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