The correlation between serum levels and placental tissue expression of PLGF and sFLT-1 and the FIGO grading of the placenta accreta spectrum disorders.

Letizia Alessandrini,Rozi Aryananda,Grace Ariani, Betty Agustina,Muhammad Ilham Aldika Akbar,Erry Gumilar Dachlan, Gustaff Dekker,Ernawati Ernawati

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians（2023）

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摘要

There are differences in PAS's angiogenic processes according to the severity of trophoblast cell invasion. But there is no overall correlation between serum levels and PLGF and sFlt-1 expression in the placenta, suggesting the imbalance between angiogenic and anti-angiogenic are local mechanisms in the placental and the uterine wall.

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FIGO grading,PLGF,maternal health,placenta accreta spectrum,placenta previa,sFlt-1

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