Population pharmacokinetics and limited sampling strategies of polymyxin B in critically ill patients.

Meng-Ying Pi,Chang-Jie Cai,Ling-Yun Zuo,Jun-Tao Zheng, Miao-Lun Zhang,Xiao-Bin Lin,Xiao Chen,Guo-Ping Zhong,Yan-Zhe Xia

The Journal of antimicrobial chemotherapy（2023）

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摘要

A dosing regimen should be based on body weight and the application of CRRT. A two-sample strategy for therapeutic drug monitoring could facilitate individualized treatment with polymyxin B in critically ill patients.

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