Incidence of breakthrough fungal infections on isavuconazole prophylaxis compared to posaconazole and voriconazole.

Transplant infectious disease : an official journal of the Transplantation Society(2023)

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摘要
Patients who received isavuconazole prophylaxis during AML induction therapy or post-HCT experienced a similar incidence of breakthrough fungal infections compared to those who received posaconazole or voriconazole. These results suggest no difference in antifungal prophylactic efficacy; however larger prospective comparative studies are needed.
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关键词
AML,acute myeloid leukemia,alloHSCT,fungal prophylaxis,isavuconazole,posaconazole,stem cell transplant,voriconazole
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