Prioritizing sufficient dose to gross tumor volume over normal tissue sparing in intensity-modulated radiotherapy treatment of T4 nasopharyngeal carcinoma.

Yanyan Chen,Quxia Zhang,Tianzhu Lu,Cairong Hu,Jingfeng Zong,Yun Xu,Wei Zheng,Lisha Chen,Senan Lin,Sufang Qiu,Luying Xu,Jianji Pan,Qiaojuan Guo,Shaojun Lin

Head & neck（2023）

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摘要

Our retrospective review showed that its feasible to maximize gross tumor volume dose coverage while exceeding most CNS OAR constraint standards, with ideal local control and no obvious increase of craniocerebral toxicity.

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关键词

head and neck cancer,nasopharyngeal carcinoma,organs at risk,radiation tolerance,targeted radiation therapy,temporal lobe

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