Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+ CAFs in intrahepatic cholangiocarcinoma.

Clinical and translational medicine(2023)

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摘要
ARBs exhibit anti-fibrotic function by inhibiting the viability of CAFs. These findings support using ARBs as a novel therapeutic option for targeting iCCA.
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关键词
AGTR1,MFAP5,angiotensin receptor blockers,cancer-associated fibroblasts,intrahepatic cholangiocarcinoma
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