Clinical applications of the respiratory equation of motion to guide decision-making in the patient under invasive mechanical ventilation

Javier Mancilla-Galindo, Carlos Mendiola-Villalobos,Daniel Carrion-Moya Jorge,Ivan Zamarron-Lopez Eder, Alberto Guerrero-Gutierrez Manuel,Ernesto Deloya-Tomas,Salvador Sanchez-Diaz Jesus,Diego Escarraman-Martinez, Israel Vasquez-Cuellar Adolfo,Ashuin Kammar-Garcia, Raul Soriano-Orozco, Alberto Castanon-Gonzalez Jorge,Federico Gordo-Vidal,Ruben Perez-Nieto Orlando

IATREIA(2023)

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摘要
Introduction: Mechanical ventilation is a common practice in intensive care units and anesthesiology with both therapeutic and potentially har-mful implications for the respiratory system and distant organs, that is why it is of utmost importance to continually monitor ventilation parameters.Objective: To describe the equation of motion of the respiratory system and its clinical applications in the patient under invasive mechanical ven-tilation.Main: The equation of motion of the respiratory system integrates the dy-namic forces generated by the ventilator with the intrinsic properties of the lung and chest wall. It expresses the pressure in the respiratory system in re-lation to volume, elastance, resistance, air flow and pressures generated by the ventilator and the patient. Elevated pressures in the respiratory system during mechanical ventilation are associated with greater mortality, that is why the identification of the components responsible for elevation of pres-sures through the equation of motion of the respiratory system allows to modify ventilator programmed parameters to maintain a protective ven-tilation.Conclusion: Decision-making based on the equation of motion of the res-piratory system allows to modify ventilatory parameters according to the characteristics and diseases of the patient under mechanical ventilation.
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关键词
Respiratory Distress Syndrome,Adult,Airway Resistance,Critical Care,Chronic Obstructive Pulmonary Disease,Pulmonary Ventilation,Respiratory Mechanics
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