Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin.

Byungwook Kim,Dha Woon Im,Heejae Won,Jung Sunwoo,Seung Seok Han,Hajeong Lee,Dong Ki Kim,Kook-Hwan Oh,Kwon Wook Joo,Yon Su Kim,Joo-Youn Cho,SeungHwan Lee,Jaeseong Oh,In-Jin Jang,Yong Chul Kim

Diabetes, obesity & metabolism（2023）

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摘要

The effect of HD on the PK and PD characteristics of evogliptin was not clinically significant; therefore, dose adjustment according to HD status is not necessary.

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关键词

DPP-4 inhibitor,diabetes mellitus,end-stage renal disease,haemodialysis,pharmacodynamics,pharmacokinetics

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