LncRNA INPP5F ameliorates stress-induced hypertension via the miR-335/Cttn axis in rostral ventrolateral medulla.

Shuai Zhang,Gaojun Chen,Xueping Wang,Lei Tong,Linping Wang,Tianfeng Liu,Liucun Zhu,Shumin Zhou,Haisheng Liu,Dongshu Du

CNS neuroscience & therapeutics（2023）

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摘要

LncRNA INPP5F was a key factor that inhibited SIH progression, and the identified lncRNA INPP5F/miR-335/Cttn/PI3K-AKT/apoptosis axis represented one of the possible mechanisms. LncRNA INPP5F could serve as a therapeutic target for SIH.

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关键词

Cttn,lncRNA INPP5F,miR-335,rostral ventrolateral medulla,stress-induced hypertension

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