Proactive and Integrated Management and Empowerment in Parkinson's Disease protocol for a randomised controlled trial (PRIME-UK) to evaluate a new model of care.

Fiona E Lithander,Emma Tenison,Jan Ypinga,Angelika Halteren,Matthew D Smith,Katherine Lloyd,Edward W Richfield,Danielle E Brazier,Mícheál Ó Breasail,Agnes J Smink,Chris Metcalfe,William Hollingworth,Bas Bloem,Marten Munneke,Yoav Ben-Shlomo,Sirwan K L Darweesh,Emily J Henderson

Trials（2023）

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摘要

This trial tests whether a novel model of care improves health and disease-related metrics including goal attainment and decreases hospitalisations whilst being more cost-effective than the current usual care. Subject to successful implementation of this intervention within one centre, the PRIME Parkinson model of care could then be evaluated within a cluster-randomised trial at multiple centres.

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关键词

Clinical trial,Complex intervention,Informed consent,Parkinson disease, Parkinsonian disorders,Parkinsonism,Randomised controlled trial,Research design

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