Constitutive and Induced Forms of Membrane-Bound Proteinase 3 Interact with Antineutrophil Cytoplasmic Antibodies and Promote Immune Activation of Neutrophils.
Journal of Biological Chemistry（2023）
关键词
alpha-1 protease inhibitor,anti-PR3 mAbs,autoantibody,immune activation,inflammation,neutrophil,PR3-ANCA,proteinase 3,therapeutic strategy,vasculitis
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