Outcomes Associated with Multiple Free Tissue Transfers Performed in a Single Day.

Although microvascular free tissue transfer (MFTT) remains technically challenging, surgeons may need to perform >1 MFTT operations in a given day. To compare MFTT outcomes in cases where surgeons completed one versus two flaps per day by measuring flap viability and complication rates. A retrospective review was conducted of MFTT cases from January 2011 to February 2022 with >30-day follow-up. Outcomes, including flap survival and operating room takeback, were compared using multivariate logistic regression analysis. Of 1096 patients meeting inclusion criteria (1105 flaps), there was a male predominance ( = 721, 66%). Mean age was 63.0 ± 14.4 years. Complications requiring takeback were identified in 108 flaps (9.8%) and were greatest for double flaps in the same patient (SP) (27.8%,  = 0.06). Flap failure occurred in 23 (2.1%) cases and was also greatest for double flaps in the SP (16.7%,  = 0.001). Takeback ( = 0.06) and failure ( = 0.70) rates were not different between days with one versus two unique patient flaps. Among patients undergoing MFTT, those treated on days in which surgeons perform two unique cases compared with single cases will demonstrate no difference in outcomes, as measured by flap survival and takeback, whereas patients with defects requiring multiple flaps will experience greater takeback and failure rates.