"Saving lives with nirmatrelvir/ritonavir one transplant patient at a time".

Katherine A Belden,Sarah Yeager,Jamie Schulte,Maria P Martinez Cantarin,Sean Moss,Tricia Royer,Dagan Coppock

Transplant infectious disease : an official journal of the Transplantation Society（2023）

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摘要

While administration of nirmatrelvir/ritonavir resulted in a significant increase in tacrolimus concentration, this did not result in significant nephrotoxicity. Early oral antiviral treatment in SOT recipients is feasible with medication management, even with limited tacrolimus trough monitoring.

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COVID-19,SARS-CoV-2,nirmatrelvir/ritonavir,solid organ transplantation,tacrolimus

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