Neuro-Cardio-Autonomic Modulations in Children with Duchenne Muscular Dystrophy.

Ganagarajan Inbaraj,Krishnamurthy Arjun,Adoor Meghana,Veeramani Preethish-Kumar,Anu P John,Kiran Polavarapu,Saraswati Nashi,Deepha Sekar,Kaviraja Udupa,Parthipulli V Prathuysha,Krishna Prasad,Mainak Bardhan,Trichur R Raju,Boris W Kramer,Atchayaram Nalini,Talakad N Sathyaprabha

Journal of neuromuscular diseases（2023）

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摘要

This study demonstrates a distinct early impairment of neuro-cardio-autonomic regulation in DMD. Simple yet effective non-invasive techniques such as HRV, BPV, and BRS may help identify cardiac dysfunction in a pre-clinical state, paving the way for early cardio-protective therapies and limiting disease progression in DMD patients.

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关键词

Duchenne muscular dystrophy,autonomic modulation,baroreflex sensitivity,blood pressure variability,heart rate variability

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