Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.

Fan Jiang,Yaoyi Guo,Liang Hu,Mengxue Zhang, Jieqiong Meng,Yanna Si,Hongwei Shi

Brain research（2023）

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摘要

This study suggests that NFAT1 downregulation attenuates sepsis-induced behavioral deficits by inhibiting autophagy, microglia polarization, and neuroinflammation..

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关键词

Autophagy,Hippocampus,NFAT1,Neuroinflammation,Sepsis-associated encephalopathy

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