Association between Tumor Mutational Burden, Stromal CD8 + Tumor-Infiltrating Lymphocytes, and Clinical Factors in Cervical Cancers Treated with Radiotherapy.

Hanguang Ruan,Takahiro Oike,Hiro Sato,Ken Ando,Tatsuya Ohno

Cancers（2023）

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摘要

These data indicate independence of TMB and CD8TIL density and the involvement of ARID1A alterations in antitumor immune responses in patients with cervical cancers treated with radiotherapy, warranting further mechanistic research and prospective validation.

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关键词

ARID1A,CD8+ tumor-infiltrating lymphocyte,cervical cancer,immune response,radiotherapy,tumor mutational burden

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