Transfer of Cardiac Mitochondria Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in a Preclinical Model of Ischemic Heart Disease.

Marie-Luce Vignais, Jennyfer Levoux,Pierre Sicard, Khattar Khattar,Catherine Lozza,Marianne Gervais, Safia Mezhoud,Jean Nakhle,Frederic Relaix,Onnik Agbulut,Jeremy Fauconnier,Anne-Marie Rodriguez

Cells（2023）

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摘要

The preconditioning of MSCs with the artificial transfer of cardiac mitochondria appears to be promising strategy to improve the efficacy of MSC-based cell therapy in ischemic heart disease.

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关键词

cell therapy,mesenchymal stem cells,metabolism,mitochondria transfer,post-ischemic heart failure

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