Conversion of M1 Macrophages to Foam Cells: Transcriptome Differences Determined by Sex.

Rafael Nambo-Venegas,Berenice Palacios-González,Jaime Mas-Oliva, Ana Karen Aurioles-Amozurrutia,Armando Cruz-Rangel,Abel Moreno,Alfredo Hidalgo-Miranda,Mauricio Rodríguez-Dorantes,Felipe Vadillo-Ortega,Juan Xicohtencatl-Cortes, María Isabel Ruiz-Olmedo,Juan Pablo Reyes-Grajeda

Biomedicines（2023）

引用 1|浏览21

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摘要

During LDL internalization, male monocyte-derived M1 macrophages display more marked proinflammatory gene expression. In contrast, female M1 macrophages display a more significant number of markers associated with cell damage.

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关键词

LDL internalization,M1 macrophages,atherosclerosis,chromosome Y,female,sex-related,transcriptional profile

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